NANOtechnology, GIGAntic Impact

Bright field TEM images of two metallized nanopores

Photo credit : 10.1002/adfm.201402468

On October 3, 2017, two patents were granted in the United States to the University of Ottawa’s research community. The news demonstrates one of the core services offered by Innovation Support Services who assists researchers develop, protect and commercialize their discoveries.

Together, the two patents designate a new, automated, cost-efficient, dependable and accurate way to create and control the size of a nanopore in a membrane. These new techniques offer a new alternative to existing solid-state nanopore technologies that suffer from several drawbacks that limit their usefulness for biomolecular studies. In the future, the discoveries will facilitate academic research as well as increase the potential for commercialization of any new nanopore-based technology for health science applications. These revelations can be extended to other materials all the while contributing to various applications for personalized genomics and DNA sequencing.

Fabrication of nanopores using high electric fields

  • Inventors: Wing Hei Kwok, Vincent Tabard-Cossa, Kyle Alexander Zarkel Briggs.

Method for controlling the size of solid-state nanopores.

  • Inventors: Michel Godin, Eric Beamish, Vincent Tabard-Cossa, Wing Hei Kwok.

The Godin laboratory and the T.-Cossa Laboratory played key roles in the invention process, and are both part of the University of Ottawa’s Centre for Interdisciplinary Nanophysics. The Godin Laboratory aims to develop new sensing technologies for the detection of biological material in hopes of improving the technology used for environmental monitoring, disease diagnosis and cancer detection. The T.-Cossa LAB is dedicated to the development of novel techniques and methods to manipulate and characterize single-molecules using nanofluidic devices, to unravel the basic physics governing the behaviour of biological molecules in nanoconfined geometries, and ultimately to translate these discoveries into new tools for the life sciences.

Innovation Support Services wishes to congratulate the inventors and continues to support further development and commercialization.

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